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Yasuko Rikihisa Selected Research

Ehrlichiosis

1/2021An intracellular nanobody targeting T4SS effector inhibits Ehrlichia infection.
1/2021Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy.
1/2020An Entry-Triggering Protein of Ehrlichia Is a New Vaccine Candidate against Tick-Borne Human Monocytic Ehrlichiosis.
1/2020Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation.
12/2011Ehrlichia chaffeensis induces monocyte inflammatory responses through MyD88, ERK, and NF-κB but not through TRIF, interleukin-1 receptor 1 (IL-1R1)/IL-18R1, or toll-like receptors.
8/2010Cyclic di-GMP signaling regulates invasion by Ehrlichia chaffeensis of human monocytes.
9/2007Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate.
7/2007Virulence potential of Ehrlichia chaffeensis strains of distinct genome sequences.
10/2006Cytokine gene expression by peripheral blood leukocytes in dogs experimentally infected with a new virulent strain of Ehrlichia canis.
7/2004Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44.
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Yasuko Rikihisa Research Topics

Disease

38Infections
01/2022 - 02/2002
13Ehrlichiosis
01/2021 - 02/2002
8Anaplasmosis
10/2021 - 04/2006
5Bacterial Infections (Bacterial Infection)
01/2020 - 11/2007
2Leukemia
07/2012 - 01/2011
1Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
10/2021
1Tick-Borne Diseases (Tick-Borne Disease)
01/2020
1Emerging Communicable Diseases (Emerging Infectious Diseases)
01/2020
1Poisoning
01/2017
1Starvation
12/2012
1Hepatitis
12/2011
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
12/2011
1Human Influenza (Influenza)
12/2011
1Hypersensitivity (Allergy)
08/2008
1Zoonoses
07/2007
1Bites and Stings (Sting)
02/2004

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
12/2021 - 02/2002
7CholesterolIBA
10/2021 - 09/2003
7Small Interfering RNA (siRNA)IBA
01/2019 - 11/2007
5Membrane Proteins (Integral Membrane Proteins)IBA
12/2007 - 08/2002
4Messenger RNA (mRNA)IBA
03/2009 - 09/2002
3Type IV Secretion SystemsIBA
01/2021 - 11/2007
3AntibodiesIBA
01/2017 - 03/2006
3CytokinesIBA
07/2012 - 09/2002
3Interleukin-8 (Interleukin 8)IBA
12/2011 - 09/2002
3Phosphotransferases (Kinase)IBA
02/2009 - 08/2006
2Carrier Proteins (Binding Protein)IBA
10/2021 - 12/2012
2flotillinsIBA
10/2021 - 01/2019
2LipidsIBA
10/2021 - 11/2003
2Deoxyribonucleases (DNase)FDA Link
01/2020 - 01/2013
2Histidine (L-Histidine)FDA Link
11/2014 - 08/2006
2Lipoproteins (Lipoprotein)IBA
09/2013 - 08/2008
2LipopolysaccharidesIBA
12/2011 - 10/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2011 - 09/2002
2Pattern Recognition ReceptorsIBA
01/2011 - 02/2004
2N,N'- dipyridoxylethylenediamine- N,N'- diacetic acid (PLED)IBA
08/2010 - 02/2009
2DNA (Deoxyribonucleic Acid)IBA
08/2008 - 02/2002
2Tyrosine (L-Tyrosine)FDA Link
11/2007 - 02/2002
116S Ribosomal RNAIBA
01/2022
1SterolsIBA
10/2021
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
10/2021
1Ezetimibe (Zetia)FDA Link
10/2021
1IronIBA
01/2021
1Virulence Factors (Pathogenicity Factors)IBA
01/2021
1Single-Domain AntibodiesIBA
01/2021
1salicylhydroxamic acid (SHAM)IBA
01/2020
1AntigensIBA
01/2020
1Bacterial Proteins (Bacterial Protein)IBA
01/2020
1Glycoproteins (Glycoprotein)IBA
01/2020
1VaccinesIBA
01/2020
1Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
01/2020
1oxidized low density lipoproteinIBA
01/2019
1CyclodextrinsIBA
01/2019
1LDL CholesterolIBA
01/2019
1Sequestering AgentsIBA
01/2019
1Surface Antigens (Surface Antigen)IBA
01/2017
1Peptide Nucleic AcidsIBA
01/2017
1Guanosine Triphosphate (GTP)IBA
11/2016
1Huntingtin ProteinIBA
11/2016
1GTPase-Activating Proteins (GTPase-Activating Protein)IBA
11/2016
1Heterogeneous-Nuclear Ribonucleoprotein KIBA
11/2015
1Methionine SulfoximineIBA
11/2014
1Proline (L-Proline)FDA Link
11/2014
1Protamines (Protamine Sulfate)FDA Link
11/2014
1Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
11/2014
1Glutamic Acid (Glutamate)FDA Link
11/2014
1Glutamine (L-Glutamine)FDA Link
11/2014
1proline transporterIBA
11/2014
1Beclin-1IBA
12/2012
1TOR Serine-Threonine KinasesIBA
12/2012
1Immunoglobulin G (IgG)IBA
12/2011
1Interleukin-12 (IL 12)IBA
07/2011
1Interferon-gamma (Interferon, gamma)IBA
07/2011
1manumycinIBA
06/2011
1Mitogen-Activated Protein KinasesIBA
06/2011
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
06/2011
1ProteomeIBA
01/2011
1Sterol Regulatory Element Binding ProteinsIBA
03/2009
1MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA
03/2009
13' Untranslated Regions (3' UTR)IBA
03/2009
1bis(3',5')-cyclic diguanylic acidIBA
02/2009
1diguanylate cyclaseIBA
02/2009
1Histidine KinaseIBA
02/2009
1Anti-Bacterial Agents (Antibiotics)IBA
12/2008
1Rifampin (Rifampicin)FDA LinkGeneric
12/2008
1Doxycycline (Periostat)FDA LinkGeneric
09/2007
1Peptidoglycan (Murein)IBA
07/2007
1EndotoxinsIBA
07/2007
1ChemokinesIBA
05/2007
1Apolipoproteins E (ApoE)IBA
05/2007
1Interleukin-8B ReceptorsIBA
05/2007
1ApolipoproteinsIBA
05/2007
1Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA
05/2007
1CaspasesIBA
09/2006
1Inhibitor of Apoptosis ProteinsIBA
09/2006
1Caspase 9IBA
09/2006
1closantelIBA
08/2006
1EpitopesIBA
03/2006
1Complementary DNA (cDNA)IBA
02/2004

Therapy/Procedure

2Therapeutics
01/2021 - 01/2020